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ADRENAL MEDULLARY TUMOR (PHEOCHROMOCYTOMA) AND DIABETES MELLITUS; DISAPPEARANCE OF DIABETES AFTER REMOVAL OF THE TUMOR*

LEROY E. DUNCAN JR., M.D.; JAMES H. SEMANS, M.D.; and JOHN EAGER HOWARD, M.D.
Ann Intern Med. 1944;20(5):815-821. doi:10.7326/0003-4819-20-5-815
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The clinical picture associated with tumors composed of tissue morphologically and functionally similar to that of the adrenal medulla has been fairly well defined.1, 2, 3 The cardinal feature of this entity is hypertension, usually paroxysmal. As one would expect, there is frequently evidence that carbohydrate metabolism is abnormal. We have recently observed a patient with an adrenal pheochromocytoma in whom the disturbance of carbohydrate metabolism was so severe that he was followed for several years in our Diabetic Clinic as a characteristic case of diabetes mellitus. Even after the diagnosis of pheochromocytoma had been established, it was thought that

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