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Ann Intern Med. 1945;22(5):746-748. doi:10.7326/0003-4819-22-5-746
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Granuloma inguinale (granuloma venereum) is a form of venereal infection which is common and widespread in the tropics, including the West Indies. Although rarely recognized in the northern United States, many cases have been observed in the southern states, particularly among the negroes. The lesions are usually limited to the genital regions and start as small vesicles or papules on the penis or labia minora, slowly spreading over the adjacent skin and mucous membranes. These lesions rupture or become excoriated, producing foul ulcerations covered with granulation tissue which may become exuberant and fungating. The lesions may be very mutilating, and


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