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THROMBOTIC THROMBOCYTOPENIC PURPURA

P. W. C.
Ann Intern Med. 1950;33(3):739-743. doi:10.7326/0003-4819-33-3-739
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Fulminating purpura hemorrhagica with profuse bleeding often presents an extremely difficult problem both as to diagnosis and treatment. Much remains to be learned about the hemorrhagic diseases, and the recent differentiation of a new clear-cut clinical and pathologic entity among the cases of "idiopathic" thrombocytopenic purpura marks a welcome advance in our knowledge of these conditions.

The first adequate report of the pathologic lesions in this disease is credited to Moschcowitz,1 who described multiple hyaline thrombi in the terminal arterioles and capillaries, widely disseminated but most abundant in the myocardium. This was in a girl of 16 who died after

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