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THE CHEMOPROPHYLAXIS OF INFECTION*

LOUIS WEINSTEIN, Ph.D., M.D., F.A.C.P.
Ann Intern Med. 1955;43(2):287-298. doi:10.7326/0003-4819-43-2-287
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This excerpt has been provided in the absence of an abstract.

The effectiveness of the antimicrobial agents in eliminating certain organisms and in curing the diseases produced by them has led to their use for the prevention of specific infectious processes, or of infection in general. The results obtained when antibiotics have been employed for this purpose have been quite variable. In some instances chemoprophylaxis has been eminently successful, in others it has failed completely, while in still others no conclusion can be reached because of the inadequacies of the available data.

Chemoprophylaxis has been used primarily for four purposes: (1) to protect healthy individuals, either singly or in groups, against

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