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Ann Intern Med. 1957;47(6):1280-1284. doi:10.7326/0003-4819-47-6-1280
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The use of cultures of human or simian tissue in roller tubes for the isolation and study of certain viruses was a technical advance of the greatest practical importance. Although its major application thus far has been in the study of the polioviruses, it has made possible the recognition of the large group of adenoviruses as agents in many cases of minor respiratory infection. In conjunction with the use of tissue cultures in examining fecal extracts for polioviruses, other viruses have been isolated which do not react with antiserum to the known polioviruses. They do, however, cause readily recognized degenerative


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