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Cancer in Families: A Study of the Relatives of 200 Breast Cancer Probands.

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By MURPHY DOUGLAS P.. , M.D., and ABBEY HELEN. , SC.D. 76 pages; 21.5 X 14 cm. Published for the Commonwealth Fund by the Harvard University Press; . 1959.. Price, $2.50.

Ann Intern Med. 1960;52(4):944. doi:10.7326/0003-4819-52-4-944_1
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This excerpt has been provided in the absence of an abstract.

One of the commonly accepted generalizations concerning the epidemiology of cancer is that this disease occurs more frequently among relatives of a person with cancer than among relatives of a person who does not have cancer. If it can be demonstrated that familial aggregation of cancer takes place, and only in certain types, strong clues concerning the etiology of cancer can follow. However, research in this area is difficult and has been characterized by serious limitations in many instances.

The authors of the report reviewed here, following an evaluation of existing studies, designed an investigation which would avoid the weaknesses


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