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Observations on Secondary Malabsorption Syndromes of Intestinal Origin: Regional Enteritis, Lymphoma, Jejunal Diverticulosis, Gastrojejunocolic Fistula

Ann Intern Med. 1961;55(3):433-447. doi:10.7326/0003-4819-55-3-433
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Malabsorption syndromes may occur in any of the diseases or conditions which impair absorption from the small intestine. It may be impaired by faulty digestion within the small intestine, by conditions that interfere directly with the process of absorption, or by abnormalities of the stomach.

A classification based on the site and mechanism of the malabsorptive defect is given in Table 1 (1, 2). The origin of the defect may be from the small intestine or its mesentery, from gastric abnormalities, from pancreatic disease leading to a pancreatic enzyme insufficiency, or from hepatobiliary conditions causing a lack of bile salts.


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