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Addison's Disease and Hyperthyroidism

WAYNE V. GREENBERG, M.D.
Ann Intern Med. 1961;55(4):663-667. doi:10.7326/0003-4819-55-4-663
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This excerpt has been provided in the absence of an abstract.

The simultaneous or sequential occurrence of several endocrinopathies in the same patient naturally stimulates speculation concerning pathophysiologic relationships and the possibility of a common etiology. Furthermore, modification of the clinical or laboratory pattern of an endocrinopathy by the presence of a second glandular dysfunction may lead to diagnostic confusion.

Despite the extensive literature concerning chronic adrenal insufficiency it is a rare entity. In the past, the majority of cases probably escaped detection due to a lack of specific diagnostic procedures. During recent years the development of reliable methods for quantitative determination of adrenal steroids, and the availability of adequate replacement

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