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Antimalarial Therapy of Lupus Erythematosus

Ann Intern Med. 1961;55(5):772-776. doi:10.7326/0003-4819-55-5-772
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The treatment of lupus erythematosus with antimalarial compounds has been pursued for almost a decade in this country. In that time, many clinicians have been impressed by the therapeutic efficacy of these drugs. Yet, only one long-term follow-up study (1) is available on which to base a judgment of the value of these drugs. We wish to report data on the results of treatment of lupus erythematosus, both discoid and systemic varieties, seen at the Mayo Clinic, in cases in which quinacrine hydrochloride (Atabrine) therapy was started in 1952 or early in 1953. Early results of treatment in some of


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