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Cat-scratch Disease: Complement Fixation and Skin Test Results

Ann Intern Med. 1961;55(6):903-910. doi:10.7326/0003-4819-55-6-903
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Recent descriptions of several large patient series emphasize that cat-scratch disease is more prevalent than originally believed (1-4). Since its recognition in 1932 by Foshay, an increasing number of cases have been reported. The syndrome, also called cat-scratch fever, nonbacterial lymphadenitis, or benign inoculation lymphorecticulosis, because of its extreme protean nature, is often confused clinically with other lymphadenopathies.

Most investigators are of the opinion that the disease is of viral etiology. However, such confirmation is lacking, as yet. Mollaret, Reilly, Bastin, and Tournier (5) reported the successful transmission of the disease to humans and monkeys by inoculation of lymph node


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