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On the Pathogenesis of Diabetic Steatorrhea

S. M. SUMI, M.D.; and J. M. FINLAY, M.D., F.R.C.P. (C), F.A.C.P.
Ann Intern Med. 1961;55(6):994-997. doi:10.7326/0003-4819-55-6-994
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This excerpt has been provided in the absence of an abstract.

The systemic complications of diabetes mellitus have been well described in the past (1). Intermittent, continuous, or nocturnal diarrhea, and nocturnal fecal incontinence have been noted frequently (1-4), and usually have been related to autonomic nervous system disorder. The complication of steatorrhea has had much less attention until recently.

Many etiological factors have been suggested to explain these gastrointestinal findings in the past. Vitamin deficiency, particularly of the B group, has been suggested by some (3), based on their success in treatment of the condition with vitamin B12 and liver extract. It is generally agreed that deficiency of external pancreatic


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