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Idiopathic Hypoparathyroidism: Follow-up Study Including Autopsy Findings of a Case Previously Reported

Ann Intern Med. 1962;56(3):484-487. doi:10.7326/0003-4819-56-3-484
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Idiopathic hypoparathyroidism is sufficiently uncommon to be worth reporting, particularly if associated with unusual features. A patient who was described by Kopin and Rosenberg (1) and who fulfilled the criteria of idiopathic hypoparathyroidism was studied at autopsy; one gland was found containing apparently normal parathyroid tissue. These authors pointed out that of 108 previously reported cases satisfying the criteria of diagnosis of idiopathic hypoparathyroidism, only seven had had autopsies performed. In most of these, absence of the parathyroid glands was reported, and in only one instance were scattered parenchymal cells noted to be associated with fatty replacement of the glands.


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