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Clinical Features of Pheochromocytoma.

R. W. Gifford Jr., M.D. (Assoc.); W. F. Kvale, M.D., F.A.C.P.; F. T. Maher, M.D.; G. M. Roth, Ph.D.; and J. T. Priestley, M.D.
Ann Intern Med. 1962;56(4):667. doi:10.7326/0003-4819-56-4-667_2
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A review of 71 cases of pheochromocytoma, diagnosed antemortem at the Mayo Clinic, revealed that the diagnosis was strongly suspected clinically before any confirmatory tests were performed in 65 cases. Salient features in the history included headache (83%), diaphoresis (74%), palpitations (65%), pallor (46%), nervousness (46%), and tremulousness (41%). These symptoms frequently occurred paroxysmally even though hypertension was sustained. Hypertension was paroxysmal in 35 cases, persistent in 35, and absent in one case in which the only symptom was profuse, persistent perspiration. Of 35 patients with paroxysmal hypertension, 17 were men and five of these were physicians! Of 36 patients


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