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Abstracts |

Secondary Gout.

A. B. Gutman, M.D., F.A.C.P.; and T. F. Yu, M.D.
Ann Intern Med. 1962;56(4):675. doi:10.7326/0003-4819-56-4-675_1
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Ordinarily a genetically transmitted primary disease, gout occasionally is acquired, as a complication particularly of chronic hemopoietic disorders in which there is augmented turnover of nucleic acids and excessive formation of uric acid. Of 27 such cases encountered and classified as secondary gout in the past ten years, 22 developed in the course of polycythemia vera, myeloid metaplasia, or both. The ensuing clinical picture of acute arthritis responsive to colchicine and tophaceous deposits closely resembles primary gout, but there are some differences. A familial history of gout was obtained in only one case. Onset of overt gout occurred late in




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