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Kidney Biopsy in Chronic Bacteriuria and Pyelonephritis.

C. McC. Smythe, M.D. (Assoc.); and F. A. McIver, M.D.
Ann Intern Med. 1962;56(4):698-699. doi:10.7326/0003-4819-56-4-698_2
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Fifty-four biopsies from 47 patients encompassing all stages of urinary infection from asymptomatic bacteriuria to terminal chronic pyelonephritis have been studied. Clinical classification was in four groups: I. Asymptomatic bacteriuria without any history of urinary tract infection; II. Asymptomatic bacteriuria with a previous history of urinary tract infection; III. Currently symptomatic urinary tract disease; and IV. Systemic symptoms of advanced renal disease. In the four groups, biopsy showed significant evidence of pyelonephritis in four of eight from group I, ten of 28 from group II, four of 12 from group III, and three of six from group IV. In six


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