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Nephrolithiasis as a Complication of Ulcerative Colitis and Regional Enteritis

JULIUS J. DEREN, M.D.; JEROME G. PORUSH, M.D.; MARVIN F. LEVITT, M.D., F.A.C.P.; and MANSHO T. KHILNANI, M.D.
Ann Intern Med. 1962;56(6):843-853. doi:10.7326/0003-4819-56-6-843
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The coexistence of gastrointestinal disease and renal calculi has been noted in few clinical entities. Calcium urolithiasis and upper gastrointestinal symptoms with occasional frank peptic ulceration often present as associated manifestations of primary hyperparathyroidism (1). The development of nephrocalcinosis after prolonged treatment of chronic peptic ulcer with absorbable alkali and a milk diet is also well documented (2). Apart from these syndromes, a well defined association between renal lithiasis and disorders of the digestive tract has been reported infrequently.

Among the complications developing during the course of ulcerative colitis and regional enteritis, urolithiasis has received little attention. Jankelson, McClure, and

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