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Jaundice as an Early Manifestation of Scarlet Fever: Report of Three Cases in Adults and Review of the Literature

Ann Intern Med. 1962;57(1):60-72. doi:10.7326/0003-4819-57-1-60
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Jaundice as a manifestation of scarlet fever rarely has been recorded in the American and English literature. Osler in 1900 (1) and Crandall in 1920 (2) did not mention it, which is a particularly interesting omission in view of the greater severity of scarlet fever in their era. Similarly, recent texts and reviews have not mentioned this clinical combination (3-12). Descriptions of jaundice occurring with scarlet fever emphasize its occurrence after the second week rather than during the acute phase of the exanthem (13).

Within one year, 3 adults whose onset of scarlet fever was associated with jaundice were observed


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