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Celiac Disease: Problems in Diagnosis and Effects of a Gluten Free Diet

D. J. BUCHAN, M.D., F.R.C.P.(C); and J. W. GERRARD, D.M., M.R.C.P.(L), F.R.C.P.(C)
Ann Intern Med. 1962;57(1):85-95. doi:10.7326/0003-4819-57-1-85
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Two recent advances in the knowledge of celiac disease have resulted in greatly increased interest in this disease. The first was the demonstration of the role of wheat gluten in producing steatorrhea in celiac children (1) and the subsequent use of a gluten free diet in the successful treatment of this disease in children and of idiopathic steatorrhea or non-tropical sprue in the adult (2-5). The response of patients with idiopathic steatorrhea to a gluten free diet suggests a similarity between the 2 diseases and, indeed, some think them to be identical and call non-tropical sprue or idiopathic steatorrhea adult


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