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Addison's Disease Secondary to Carcinoma of the Breast

Ann Intern Med. 1962;57(3):464-467. doi:10.7326/0003-4819-57-3-464
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Adrenal hypocorticism as the result of metastatic carcinoma occurs rarely. Thomas Addison included 4 such cases in his original report (1) of the syndrome now bearing his name. Of these 4 cases, only one had bilateral adrenal involvement, a 60-year-old woman with carcinoma of the breast. In the years since Addison's report, there have been a few dozen similar cases recorded, but none of them has been well documented by laboratory and pathological findings. The following case is reported because it includes just such documentation.

CASE REPORT: An 80-year-old childless housewife entered the hospital October 11, 1960, because of weakness


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