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The "Lupoid Hepatitis" Syndrome: Report of a Case Followed by Serial Liver Biopsies

Ann Intern Med. 1962;57(6):988-994. doi:10.7326/0003-4819-57-6-988
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Recurrent hepatitis with high serum gamma globulin and positive lupus erythematosus cell reactions in the blood has stimulated much comment in recent years since the first descriptions in 1955 and 1956 (1, 2). The following report describes a case of "lupoid hepatitis" followed by serial needle biopsies of the liver during 2 episodes of relapse and subsequent remissions.

CASE REPORT: A 45-year-old white female was first admitted to Presbyterian Hospital, Denver, Colorado, with jaundice on August 25, 1958. She had noticed symptoms on May 14, 1958, when she developed anorexia, lethargy, malaise, and upper abdominal pain. Five days later the



biopsy ; hepatitis ; liver

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