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Supravalvular Aortic Stenosis: Clinical Experiences with Ten Patients Including Occurrences in Two Families.

C. F. Wooley, M.D.; C. V. Meckstroth, M.D.; H. Sirak, M.D.; D. M. Hosier, M.D.; and W. Molnar, M.D.
Ann Intern Med. 1963;58(4):714. doi:10.7326/0003-4819-58-4-714_2
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This excerpt has been provided in the absence of an abstract.

Clinical recognition of supravalvular aortic stenosis causing left ventricular outflow obstruction is a recent event. Initially considered to be a pathologic curiosity, it is now apparent that supravalvular aortic stenosis is relatively common in patients with obstruction to left ventricular outflow.

Clinical experiences with 10 patients during a 2-year interval are presented. There were 7 males and 3 females, the youngest being 3½ years and the oldest 49 years. Two instances of familial occurrence include a mother and son in one family and a brother and sister in another.

Clinical findings included an aortic systolic ejection murmur, absence of an


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