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Abstracts |

Myotonia Dystrophica: A Clinical and Laboratory Study.

J. C. Harvey, M.D., F.A.C.P.; and C. Siegel, M.D. (Associate)
Ann Intern Med. 1963;58(4):729. doi:10.7326/0003-4819-58-4-729_2
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Among those diseases of muscle are the afflictions in which myotonia is a major symptom. Myotonic muscular dystrophy is one of these disease processes. This is a generalized process involving many tissues of the body. Eighteen patients with this disease who attend the Muscle Clinic of the Johns Hopkins Hospital have been studied extensively during the past 3 years. The clinical and laboratory studies done on these patients form the basis of this report.

There is a high incidence of twinning in this familial disorder which appears to be inherited as an autosomal dominant pattern. The cutaneous tissues, the eye,


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