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Chemistry of the Red Cell and Its Bearing on Anemias.

M. M. Wintrobe, M.D., F.A.C.P.
Ann Intern Med. 1963;58(4):733. doi:10.7326/0003-4819-58-4-733_1
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One of the most interesting of the structures of the body is the red blood corpuscle. Once regarded as an inert protoplasmic particle, it has been found, in recent years, that this structure is a veritable dynamo of activity. Studies of the energy metabolism of the red cell have revealed many aspects that are of great clinical importance, particularly with reference to hemolytic anemias. Again, studies of the main component of the red corpuscles, namely, hemoglobin, have led to a thorough understanding of the structure of this compound and of the factors necessary for its formation. Deficiency of some of


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