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Abstracts |

Clinical Manifestations of Primary Histoplasmosis.

G. L. Baum, M.D., F.A.C.P.; J. L. Friedman, M.D.; and J. Schwarz, M.D.
Ann Intern Med. 1963;58(4):733. doi:10.7326/0003-4819-58-4-733_2
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Primary infection with Histoplasma capsulatum is usually not observed clinically among children in the endemic area. Five cases have been seen in the past 3 years, however, in which the various manifestations of such infection have been documented.

All patients were children 12 years of age or under and all recovered, only one requiring amphotericin B. The clinical spectrum was of particular interest since only one case, that of a 5-month old infant, manifested widespread dissemination. Two cases of pericarditis with effusion, one case of localized pneumonia with hilar adenopathy, and one case with tracheal obstruction due to large paratracheal


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