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Acute Renal Failure Following Cholecystography.

J. F. Maher, M.D.; J. G. Setter, M.D.; and G. E. Schreiner, M.D., F.A.C.P.
Ann Intern Med. 1963;58(4):742-743. doi:10.7326/0003-4819-58-4-742_4
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Although isolated reports of acute renal failure after cholecystography have appeared, no renal biopsy studies, renal function tests, or analysis of clinical data have been performed. Clinical observations were, therefore, made on 9 patients who developed oliguria after cholecystography with histologic correlation in 6 (4 autopsy and 2 biopsy specimens). All were given oral iodinated dye, which was bunamiodyl in 8. Four were also given intravenous dye. The data favored direct nephrotoxicity rather than hypersensitivity or ischemia. Overdosage seemed more significant than underlying renal or hepatic dysfunction. Nonvisualization of the gall bladder delivering more dye to the kidneys occurred in


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