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The Relationship of "Chronic Pyelonephritis" to Chronic Potassium Deficiency

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Copyright ©, 1963, by The American College of PhysiciansThe American College of Physicians

Ann Intern Med. 1963;59(4):427-448. doi:10.7326/0003-4819-59-4-427
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Preliminary observations made in 1957, on patients chronically deficient of potassium suggested that chronic pyelonephritis was one sequel of chronic potassium deficiency (1, 2). At that time studies were also made of slides of renal tissue from such patients, which were sent to us by many colleagues in various parts of the world. In most sections "pyelonephritis" was noted. As a result of these observations, it does not seem to be unreasonable to postulate that the persistence of the multiple functional and structural derangement (Table 1, 1-20) noted in kidneys of man and animals with acute potassium deficiency might form


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