Pyridoxine-responsive anemia was first reported in a human adult by Harris, Whittington, Weisman, Jr., and Horrigan (1) in 1956. Since then a number of individual cases have been described (2-15) and several excellent reviews have been published (6, 9, 10, 14). Only 4 females with this condition have been reported (13, 14, 16, 17). This excludes Maier's case report (18), in 1957, of a female patient with a macrocytic megaloblastic anemia responsive to vitamin B6 therapy, which is unlike that of any of the group described subsequently that responded to pyridoxine therapy.
The case report below is that of a