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Pyridoxine-Responsive Anemia with Neuropathy

Ann Intern Med. 1963;59(5_Part_1):724-730. doi:10.7326/0003-4819-59-5-724
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Pyridoxine-responsive anemia was first reported in a human adult by Harris, Whittington, Weisman, Jr., and Horrigan (1) in 1956. Since then a number of individual cases have been described (2-15) and several excellent reviews have been published (6, 9, 10, 14). Only 4 females with this condition have been reported (13, 14, 16, 17). This excludes Maier's case report (18), in 1957, of a female patient with a macrocytic megaloblastic anemia responsive to vitamin B6 therapy, which is unlike that of any of the group described subsequently that responded to pyridoxine therapy.

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