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The Association of Nocardiosis and Pulmonary Alveolar Proteinosis: A Case Study

Ann Intern Med. 1964;60(2_Part_1):266-275. doi:10.7326/0003-4819-60-2-266
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This excerpt has been provided in the absence of an abstract.

Pulmonary alveolar proteinosis was first described as a disease entity in 1958 by Rosen, Castleman, and Liebow (1). Forty-seven additional cases have been reported in detail (2-36, 36A, 36B) since their original report of 27 cases.

Patients with alveolar proteinosis appear to have an increased susceptibility to pulmonary infections caused by a variety of organisms (1, 3, 15, 17, 18, 21-24, 27, 34, 37). Nevertheless, the frequent association of nocardiosis and pulmonary alveolar proteinosis (1, 15, 21, 27, 34), each a relatively uncommon disease, warrants further emphasis.

This report concerns a patient with pulmonary alveolar proteinosis and nocardiosis with dissemination


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