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Periodic Peritoneal Dialysis for Chronic Renal Failure: A Case Study of Sixteen Months' Experience

R. R. SCHUMACHER, M.D.; A. S. RIDOLFO, PH.D., M.D.; and B. L. MARTZ, M.D., F.A.C.P.
Ann Intern Med. 1964;60(2_Part_1):296-305. doi:10.7326/0003-4819-60-2-296
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This excerpt has been provided in the absence of an abstract.

The properties of the peritoneum as a dialyzing membrane were first explored as early as 1894 to 1895 (1, 2). Subsequent work enlarged upon this early knowledge and demonstrated that: [1] fluids injected into the peritoneal cavity would change in volume over a short period of time according to the concentration and nature of solutes in the dialyzing fluid (3-7); and [2] various substances would cross the peritoneum in response to concentration gradients (3, 4, 7-11). It was demonstrated that urea, uric acid, creatinine, and sulfate, as well as chlorbutanol, salicylates, and phenolphthalein (7) would migrate into fluids injected into


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