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Abstracts |

Complications of Blood Transfusion.

Lawrence E. Young, M.D., F.A.C.P.
Ann Intern Med. 1964;60(2_Part_1):326. doi:10.7326/0003-4819-60-2-326_2
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Every blood transfusion subjects the patient to hazards, some of which can be minimized by exercising necessary precautions while others cannot be reduced by methods now available. The following complications will be considered from the standpoints of incidence, pathogenetic mechanisms, and prevention: destruction of donated or autogenous red blood cells, isoimmunization with subsequent risk of hemolytic disease in offspring and increased risk of hemolytic reactions after future transfusions, reactions initiated by antibodies to leukocytes and platelets, thrombocytopenia after transfusion of large volumes of stored blood, circulatory overload, hepatitis, and toxic reactions due to use of contaminated blood.

The risks of


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