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Abstracts |

Canine Allergy: A Model of a Spontaneous Hypersensitivity Disease.

Roy Patterson, M.D., F.A.C.P.; and Jacob J. Pruzansky, Ph.D.
Ann Intern Med. 1964;60(2_Part_1):328. doi:10.7326/0003-4819-60-2-328_1
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Spontaneous pollen allergy occurs in animals and provides a model of this type of hypersensitivity useful for laboratory investigation. A colony of four dogs with spontaneous pollen allergy has been established in order to study the clinical, immunologic, and pharmacologic abnormalities in these dogs and to compare these findings with those established in the human allergic patient. Clinical manifestations during the pollen season in these dogs include conjunctivitis, dermatitis, rhinitis, and asthma. These symptoms can be reproduced under controlled conditions of exposure to the specific aeroallergen. The immediate type of wheal and erythema reactivity is present and is transferrable to


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