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Abstracts |

Intensive Immunization of Man: A Clinical and Laboratory Study.

Richard N. Peeler, M.D. (Associate); and Leighton E. Cluff, M.D., F.A.C.P.
Ann Intern Med. 1964;60(2_Part_1):328. doi:10.7326/0003-4819-60-2-328_3
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The authors have previously reported the results of clinical and laboratory investigations done in 1956 upon a group of 99 men employed in laboratories handling many pathogenic bacterial, rickettsial, and viral agents. These men had been immunized prophylactically over a period of 7 to 13 years with a variety of antigens, receiving a total of 35 to 75 ml of material. Clinical evaluation of the immunized men revealed no unusual incidence of illness. Laboratory investigations recarded a high incidence of lymphocytosis, abnormal liver function tests, and a peculiar aberration of serum electrophoretic pattern characterized by poor separation of the alpha-2




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