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Abstracts |

Multiple Endocrine Adenomatosis.

Boy Frame, M.D., F.A.C.P.; R. J. Hartstock, M.D.; and H. S. Ballard, M.D.
Ann Intern Med. 1964;60(2_Part_1):330. doi:10.7326/0003-4819-60-2-330_1
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This excerpt has been provided in the absence of an abstract.

The parathyroids, pancreatic islets, adrenals, and pituitary are the glands most frequently involved in the syndrome of multiple endocrine adenomatosis (MEA). In more than 50% of the reported cases peptic ulcer has been observed.

In a Negro family extending over five generations, 13 of 25 members had evidence of the MEA syndrome. Hyperparathyroidism was the most commonly recognized feature occurring in 10 of 13 affected members. Peptic ulcer occurred in 9 members and 5 died of complications secondary to ulcer perforation. Seven of the family were known to have one or more nonbeta islet cell adenomas, and 5 members were


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