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Vascular Purpura Due to Colchicine in a Patient with Gout

Ann Intern Med. 1964;60(3):470-473. doi:10.7326/0003-4819-60-3-470
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The purpose of this report is to present a case of purpura occurring in an individual receiving therapeutic doses of colchicine for acute gouty arthritis. Search of the literature from the present to 1920 reveals no report of this occurrence. Indeed, in a recent publication dealing with the clinical pharmacology of colchicine in the treatment of gouty arthritis, no mention is made of this untoward reaction (1).

CASE REPORT: A 33-year-old physician suddenly developed swelling and slight discomfort over the left elbow with no history of antecedent trauma. Two years previously he had experienced swelling, stiffness, and some discoloration of


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