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Cardiopulmonary Function in Young Smokers: A Comparison of Pulmonary Function Measurements and Some Cardiopulmonary Responses to Exercise Between a Group of Young Smokers and a Comparable Group of Nonsmokers

Ann Intern Med. 1964;60(4):603-610. doi:10.7326/0003-4819-60-4-603
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It has previously been reported that smokers develop a greater oxygen debt during exercise than nonsmokers (1). This investigation was designed to study the effect of chronic cigarette smoking on the accumulation and repayment of oxygen debt during exercise and on some aspects of pulmonary function and to evaluate the possible correlation of the increased oxygen debt with pulmonary function abnormalities. The studies were carried out in young men who were similar in body surface area, age, and occupation.

Extensive pulmonary function studies including pulmonary diffusing capacity for carbon monoxide (DL) as well as oxygen consumption and heart rate were


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