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Abstracts |

A Critical Review of Studies on Long-term Anticoagulant Therapy After Myocardial Infarction.

Richard V. Ebert, M.D.
Ann Intern Med. 1964;60(4):709. doi:10.7326/0003-4819-60-4-709_2
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A large number of studies have been published on the efficacy of long term anticoagulant therapy in the management of patients recovered from a myocardial infarct. Many of these studies have been criticized because of the lack of comparability of the treated and control groups. The fundamentaal problem in studies of this type is the selection of a treated and control group in such a manner that bias is avoided and that the groups are similar in composition.

Four studies will be discussed. These are the studies of the Veterans Administration, the British Medical Research Council, Bjerkelund, and Hilden. In

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