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Silent Pulmonary Emboli Without Infarction: Neovascular Formations by the Systemic Arterial Circulation of the Lung as Cause.

Roe E. Wells Jr., M.D., F.A.C.P.; and George T. Smith, M.D.
Ann Intern Med. 1964;60(4):714. doi:10.7326/0003-4819-60-4-714_1
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The problem of clinical diagnosis of pulmonary emboli is emphasized by the quantitative morphologic examinations of the lungs of patients dying of this entity, in which the terminal event has been preceded by numerous prior episodes. These were apparently unknown to both patient and physician. Despite the fact numerous emboli were found in the lungs of these patients less than 10 per cent gave rise to infarction. Experimental studies by Liebow and others who have ligated the main pulmonary arteries of the dog does not proceed to infarction because of the development of bronchial arterial-pulmonary arterial collateral circulations. Similar studies


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