0

The full content of Annals is available to subscribers

Subscribe/Learn More  >
Abstracts |

Histidinemia in Identical Twins with Speech Defect.

Maj. Billy F. Andrews; Maj. Charles R. Angel; and 1st Lt. William M. Walter Jr.
Ann Intern Med. 1964;60(4):718. doi:10.7326/0003-4819-60-4-718_2
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

As a result of mass testing for phenylketonuria in infants and retarded children with the urinary ferric chloride test, a new entity, histidinemia, was described by Ghadimi and associates in 1961. Auerbach and associates, after histidine and urocanic acid loading studies in a patient and the determination of urinary metabolites, proposed that the enzymatic defect could be in liver histidase. In the absence of conversion of histidine to urocanic acid, excessive amounts of histidine are transaminated to imidazolepyruvic acid, which is responsible for the green color reaction in the urinary ferric chloride test. La Du demonstrated absence of skin histidase

...

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Buy Now

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)