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Observations on Acute Renal Insufficiency Following Oral Cholecystography.

Ralph M. Myerson, M.D., F.A.C.P.; J. George Teplick, M.D.; and Frank J. Sanen, M.D.
Ann Intern Med. 1964;60(4):724-725. doi:10.7326/0003-4819-60-4-724_3
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Recently there has been a number of reports of serious renal impairment after the use of oral cholecystographic media. Each of four opaque media was administered to patients without evidence of renal and hepatic disease and to known cirrhotic patients. In addition, one medium was administered to 18 patients with chronic renal insufficiency.

Renal function was studied before and after the administration of the contrast media by determinations of blood urea nitrogen, blood creatinine, and creatinine clearance. Urinary output was followed and urinalyses were performed frequently. Blood pressures were determined hourly on the night of dye administration.

No alteration in


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