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The American College of Physicians Honorary Fellowship Lecture: The Prospects for Transplantation in Man.

Peter Medawar, M.D.
Ann Intern Med. 1964;60(4):730. doi:10.7326/0003-4819-60-4-730_1
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There are now clear signs that the immunological barrier which normally prohibits the transplantation of tissues and organs between one human being and another can be circumvented or broken down. The success of kidney homografts in clinical practice, in the few cases in which they have been successful, has been due to a combination of surgical skill, attentive medical care, the judicious use of immunosuppressive agents, and great good luck—the element of luck being the accidental choice of a relatively compatible organ donor. It is of paramount importance to devise a method by which, whenever any choice is possible, the


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