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Abstracts |

Neurofibromatosis and Cystic Lung Disease.

Donald Massaro, M.D.; and Sol Katz, M.D., F.A.C.P.
Ann Intern Med. 1964;60(4):735-736. doi:10.7326/0003-4819-60-4-735_3
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Von Recklinghausen's disease is known to affect many systems and organs in addition to the usual neurocutaneous findings. Thoracic involvement most commonly presents as neuromatous tumors of the posterior mediastinium. In addition, the lungs may be involved by benign neurofibroma or by metastatic disease in those cases where the neurofibroma have become sarcomatous. We have recently encountered four cases of classical von Recklinghausen's neurofibromatosis, all proven by biopsy, who have in addition cystic lung disease. To our knowledge, this association has not been described in the American literature.

The chest film of the first patient revealed linear fibrosis, honeycombing and


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