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Abstracts |

Approaches to the Chemotherapy of Virus Infections.

Igor Tamm, M.D.; and Hans J. Eggers, M.D.
Ann Intern Med. 1964;60(4):731. doi:10.7326/0003-4819-60-4-731_1
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Recent years have seen two new developments which bear on the broad problem of the chemotherapy of virus infections. Selective inhibition of viral replication by chemical compounds has been demonstrated with a number of viruses, and the first successes in the chemotherapy and chemoprophylaxis of viral infections in man have been recorded. Of equal significance is the discovery that viruses direct the synthesis in virus-infected cells of new enzymes which function in the synthesis of the viral genetic material, which may be deoxyribonucleic or ribonucleic acid. Both the viral genetic material and the virus-directed enzymes represent suitable targets for selective


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