The full content of Annals is available to subscribers

Subscribe/Learn More  >
Abstracts |

Significance of Antibody to DNA in Systemic Lupus Erythematosus.

George J. Friou, M.D., F.A.C.P.; Salvador P. Casals, M.D.; Lynn Myers, M.D.; and Perry O. Teague, M.D.
Ann Intern Med. 1964;60(4):741. doi:10.7326/0003-4819-60-4-741
Text Size: A A A
This excerpt has been provided in the absence of an abstract.

Study of antinuclear and other antitissue antibodies has contributed to the increasing interest in concepts of immunologic mechanisms of pathogenesis of mesenchymal diseases, especially systemic lupus erythematosus. In spite of this, there has been no clinical or direct experimental evidence relating any of the antinuclear antibodies to specific disease manifestations.

It has been our contention that the significance of antinuclear antibodies can only be properly elucidated by studies which distinguish between individual factors. To facilitate distinction of antibodies with different specificities we have previously described a spot test for detection of antibody to nucleoprotein, and a characteristic nuclear reaction pattern


First Page Preview

View Large
First page PDF preview





Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $42.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Related Articles
Journal Club
Related Point of Care
Topic Collections
PubMed Articles
Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.