Gastrointestinal manifestations in patients with lupus erythematosus are common and may include dysphagia, anorexia, nausea, vomiting, diarrhea, hemorrhage, and abdominal pain of varying severity (1). Abdominal distress in this disease has been associated with peritonitis, ileus, perihepatitis, perisplenitis, "lupoid hepatitis," pancreatitis, and intestinal ulceration or perforation (2-4). The association of ulcerative colitis or regional enteritis with discoid or systemic lupus erythematosus, or both, has been noted infrequently (2, 5, 7). Five such patients currently are under observation at the University of Chicago and are described in this paper.
CASE REPORTS: CASE 1. DISCOID AND POSSIBLY SYSTEMIC LUPUS ERYTHEMATOSUS WITH PROBABLE