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A Clinical Evaluation of the D-Xylose Tolerance Test

JOHN M. FINLAY, M.D., F.R.C.P. (C), F.A.C.P.; JEAN HOGARTH, M.D., F.R.C.P. (C); and KEITH J. R. WIGHTMAN, M.D., F.R.C.P. (C), F.A.C.P.
Ann Intern Med. 1964;61(3):411-422. doi:10.7326/0003-4819-61-3-411
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This excerpt has been provided in the absence of an abstract.

The xylose tolerance test has been the subject of much investigative work and interest. Its application to the study of the malabsorption syndrome has been described in previous publications (1-14). A flattened blood curve and low renal xylose excretion characterizes the test response in active untreated idiopathic sprue in adults (7). In secondary steatorrhea, the blood curve and renal xylose excretion are usually normal unless the small bowel is excluded or extensively involved by disease (7, 9).

The data on which this paper is based include test responses observed in a group of illnesses in which defects in metabolism and




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