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Abstracts |

Prevention of Arteriosclerosis in Rabbits on a Hypercholesterolemic Diet by Ileal Bypass.

Henry Buchwald, M.D.
Ann Intern Med. 1964;61(4):798-799. doi:10.7326/0003-4819-61-4-798_3
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A group of 12 New Zealand white rabbits with an average whole blood cholesterol of 86 mg/100 ml and a group of 6 New Zealand white rabbits, which had previously undergone ileal bypass and had an average whole blood cholesterol of 69 mg/100 ml, were simultaneously placed on a 2% cholesterol diet for 4 months. The ileal by-pass was performed from the bowel midpoint to the cecum and therefore excluded the distal five-sixths of the ileum, as well as the ileocecal valve. At the end of the 4-month test period, the nonoperated group had a whole blood cholesterol average of


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