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Abstracts |

Carcinoma of the Colon and Chronic Ulcerative Colitis.

Richard C. Farmer, M.D.; Roberto J. Diaz, M.D.; and Charles H. Brown, M.D., F.A.C.P.
Ann Intern Med. 1964;61(4):805. doi:10.7326/0003-4819-61-4-805_2
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Among 1,258 patients with chronic ulcerative colitis seen at the Cleveland Clinic from 1950 through 1963, 24 had colonic carcinoma, an over-all incidence of 1.9%. Of the 24 patients, 15 died of the malignancy, and 1 died of unrelated causes The mean age of onset of colitis among those with carcinoma was 22.5 years; the mean age of diagnosis of colonic carcinoma was 40.7 years; and the mean duration of colitis prior to discovery of carcinoma was 18.3 years. For the 15 who succumbed from carcinomatosis, the mean age of death was 42.4 years. The mean follow-up period for the


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