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Monoamine-oxidase Inhibitor Reactions Simulating Phenochromocytoma Attacks

Ann Intern Med. 1964;61(5_Part_1):924-927. doi:10.7326/0003-4819-61-5-924
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This excerpt has been provided in the absence of an abstract.

Monoamine-oxidase (MAO) inhibitors have been increasingly prescribed for depression since 1959. Informal estimates state that under current practices 40% of hospitalized psychiatric patients receive them at some time. Many ambulatory patients receive them as well, perhaps a greater total number than patients in institutions. Adverse reactions must be uncommon in view of the great number of treated patients, yet there have been many reports of severe reactions recently.

Tranylcypromine (Parnate®) was recommended about 1960 in the U. S. A. as the most useful of these drugs (1). This compound resembles the sympathomimetic amines in chemical structure. Its ability to potentiate


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