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Changes in Cardiopulmonary Functions Related to Abstinence from Smoking: Studies in Young Cigarette Smokers at Rest and Exercise at 3 and 6 Weeks of Abstinence

RICHARD A. KRUMHOLZ, M.D.; ROBERT B. CHEVALIER, M.D.; and JOSEPH C. ROSS, M.D.
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Copyright ©, 1965, by The American College of PhysiciansThe American College of Physicians


Ann Intern Med. 1965;62(2):197-207. doi:10.7326/0003-4819-62-2-197
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Physiologic pulmonary changes associated with smoking are important from many points of view. Previously studies evaluating lung function and exercise oxygen dynamics have been performed in smokers (1-19). Many of these studies have been concerned with the acute changes after the smoking of one or two cigarettes. We recently made measurements of lung volurnes, ventilatory function, and some cardiopulmonary responses to exercise in a group of nonsmokers and found statistically significant differences between the two groups (19). Very similar results were reported by Zwi, Goldman, and Levin (18). The present study was made in order to further evaluate the pulmonary

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