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Correlation of Clinical Signs with Ventilatory Function in Obstructive Lung Disease

Ann Intern Med. 1965;62(3):477-485. doi:10.7326/0003-4819-62-3-477
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"I, for a long time, thought it very uncommon because I had observed only a few cases of it; but since I have made use of the stethoscope, I have verified its existence as well in the living as in the dead subject, and am led to consider it by no means infrequent" (1). Since this observation by Laennec nearly a century and a half ago, it has been common practice to diagnose emphysema with confidence on clinical grounds. Such faith likely was justified on the part of the maestro, but it has been our distinct impression that the modern


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